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Updated: Jun 23, 2026
06:26
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Aortic dissection due to sildenafil abuse
Selma Kenar Tiryakioglu1, Osman Tiryakioglu, Tamer Turan
1Department of Cardiology, Bursa Acibadem Hospital, Bursa, Turkey.
Interactive Cardiovascular and Thoracic Surgery
|April 24, 2009
Summary
A young man experienced a type A aortic dissection, possibly linked to sildenafil use. This rare event highlights potential risks, especially with underlying aortic conditions like bicuspid aortic valve.
Area of Science:
- Cardiology
- Vascular Surgery
- Pharmacology
Background:
- Aortic dissection is a life-threatening condition involving a tear in the aorta's inner layer.
- Sildenafil, a phosphodiesterase type 5 inhibitor, is commonly used for erectile dysfunction.
- Literature reports of sildenafil-associated aortic dissection are exceedingly rare.
Observation:
- A 28-year-old male presented with type A aortic dissection.
- The patient had a history of bicuspid aortic valve and ascending aortic aneurysm.
- Sildenafil use was noted prior to the event.
Findings:
- This case represents a potential association between sildenafil use and type A aortic dissection.
- Literature review revealed only two other similar cases, one type A and one type B dissection.
- The patient's pre-existing bicuspid aortic valve and aneurysm are significant contributing factors.
Implications:
- This case underscores the importance of considering medication history in patients with aortic dissection.
- Further research is needed to establish a definitive link between sildenafil and aortic dissection.
- Awareness of potential risks is crucial for both clinicians and patients, especially those with underlying cardiovascular conditions.
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