Developments in the serological diagnosis of opportunistic fungal infections

Recent years have seen some progress in the design of serodiagnostic tests for the medically important invasive mycoses. This has included the introduction of latex agglutination tests for antigen detection in systemic candidosis and invasive aspergillosis. The circulating cytoplasmic antigens of Candida albicans and Aspergillus fumigatus have recently been delineated as heat-shock proteins of approximate molecular weight 90 KD.