Related Experiment Video
Updated: Jun 23, 2026

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
Published on: April 7, 2023
Inflammation and NF-kappaB in Alzheimer's disease and diabetes
Ivica Granic1, Amalia M Dolga, Ingrid M Nijholt
1Department of Molecular Neurobiology, University of Groningen, Haren, The Netherlands.
Abstract:
Inflammatory processes are a hallmark of many chronic diseases including Alzheimer's disease and diabetes mellitus. Fairly recent statistical evidence indicating that type 2 diabetes increases the risk of developing Alzheimer's disease has led to investigations of the potential common processes that could explain this relation. Here, we review the literature on how inflammation and the inducible nuclear factor NF-kappaB might be involved in both diabetes mellitus and Alzheimer's disease and whether these factors can link both diseases.
Related Concept Videos
Psychoneuroimmunology: Diabetes and Cancer
Alzheimer Disease l: Introduction
NF-κB-dependent Signaling Pathway
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
Alzheimer Disease ll: Pathophysiology
Type I Diabetes II: Pathophysiology
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
