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Updated: Jun 23, 2026
The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
Published on: May 31, 2016
Determinants of time to fatigue during nonmotorized treadmill exercise
John K De Witt1, Stuart M C Lee, Cassie A Wilson
1Wyle's Life Sciences Group, Houston, Texas, USA. john.k.dewitt@nasa.gov
Abstract:
Treadmill exercise is commonly used for aerobic and anaerobic conditioning. During nonmotorized treadmill exercise, the subject must provide the power necessary to drive the treadmill belt. The purpose of this study was to determine what factors affected the time to fatigue on a pair of nonmotorized treadmills. Twenty subjects (10 men/10 women) attempted to complete 5 minutes of locomotion during separate trials at 3.22, 4.83, 6.44, 8.05, 9.66, and 11.27 kmxh. Total exercise time (
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