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Updated: Jun 23, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Symptomatic cardiac metastasis. Isolated visceral manifestation of a cutaneous malignant melanoma]
N Schwarz1, R Nebel, H-J Holzhausen
1Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Martin-Luther-Universität Halle-Wittenberg, 06097 Halle (Saale).
Abstract:
Symptomatic cardiac melanoma metastases are very rare. A 76-year-old woman was admitted because of dyspnea and intrathoracic pain 8 years after surgery of a superficial spreading melanoma and 4 years after resection of in-transit metastases. MRI and echocardiography disclosed an intracavitary right atrial mass. Histologically a cardiac melanoma metastasis was found. Unspecific cardiac symptoms in a patient with elevated risk for distant metastases of melanoma should be further investigated to discover cardiac metastasis early.
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