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Fetal demise by umbilical cord around abdomen and stricture
Shun-Jen Tan1, Chi-Huang Chen, Gwo-Jang Wu
1Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, 325 Sec. 2 Cheng-Gong Road, Nei-Hu District, Taipei, Taiwan, ROC.
Insights
Umbilical cord stricture, a common abnormality, can lead to intrauterine fetal demise (IUFD). This case highlights a fetus with stricture and entanglement, emphasizing the need for further research and surveillance in future pregnancies.
Area of Science:
- Perinatology
- Obstetrics
- Fetal Medicine
Background:
- Umbilical cord abnormalities, particularly stricture, are linked to intrauterine fetal demise (IUFD).
- Cord entanglement, while less commonly fatal, is associated with fetal growth restriction and other morbidities.
Observation:
- A 27-year-old woman presented with decreased fetal activity at 34 weeks gestation.
- Ultrasonography confirmed no fetal heart activity or blood flow.
- A demised fetus with umbilical cord stricture and abdominal entanglement was delivered.
Findings:
- The fetus weighed 1,830g, below the tenth percentile for gestational age.
- Both umbilical cord stricture and entanglement can impede fetal development.
- Umbilical cord stricture may have played a significant role in this IUFD case.
Implications:
- The etiology and sequence of events in this case remain unclear.
- Further research, including autopsy, is needed to understand these cord abnormalities.
- Patients with prior IUFD due to cord stricture require genetic counseling and close fetal surveillance in subsequent pregnancies due to recurrence risk.
Abstract:
Umbilical cord abnormalities are accepted as conditions associated with intrauterine fetal demise (IUFD), and umbilical cord stricture is most frequently encountered. In addition, although cord entanglement with multiple loops rarely increases the perinatal mortality, it is associated with a significant increase in variable kind of morbidity such as growth restriction. We describe a 27-year-old woman, with a missed abortion history at about 10 weeks' gestation in her first pregnancy, who presented to our outpatient department at 34 4/7 weeks of gestation due to decreased fetal activity during the preceding week. No fetal heart activity and blood flow had been detected by ultrasonography and pulsed-wave Doppler. A demised fetus with umbilical cord stricture and three loops around abdomen was delivered and was weighted 1,830 g that was below the tenth percentile for the gestational age. Either umbilical cord stricture or entanglement around the body can affect the development of the fetus and even be lethal. The former might play a more important role in this case. Their etiology and the sequence of the events are still undetermined, and additional evaluation such as autopsy and further research may be needed. In addition, counsel and frequent fetal surveillance should be done in patients with previous IUFD attributed to cord stricture during next pregnancy because of undetermined risk of recurrence.
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