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Published on: September 5, 2016
Thrombolytic therapy in clotted prosthetic mitral valve
S Sharma1, S K Modi, S Padmavati
1National Heart Institute, New Delhi.
The Journal of the Association of Physicians of India
|April 1, 1991
Summary
Thrombosis of a Bjork-Shiley mechanical valve in the mitral position was successfully treated with streptokinase and heparin. This effective clot lysis led to the patient remaining asymptomatic for two years post-treatment.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Thrombosis Research
Background:
- Mechanical heart valves, such as the Bjork-Shiley prosthesis, are susceptible to thrombotic events.
- Mitral valve thrombosis can lead to severe hemodynamic compromise and embolic complications.
Observation:
- Clinical suspicion of mitral valve thrombosis was confirmed using echocardiography and cine fluoroscopy.
- The patient presented with suspected thrombosis of a Bjork-Shiley valve in the mitral position.
Findings:
- Successful thrombolysis was achieved using a combination of streptokinase therapy and intravenous heparin infusion.
- The patient experienced successful lysis of the clot, resolving the thrombotic event.
Implications:
- Pharmacological thrombolysis can be a viable treatment option for Bjork-Shiley mitral valve thrombosis.
- This approach offers a potential alternative to surgical intervention, with sustained positive outcomes.
- The patient remained asymptomatic for two years, indicating the long-term efficacy of the treatment.
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