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The seizuring cat. Diagnostic work-up and therapy.

Kerry Smith Bailey1, Curtis W Dewey

  • 1Department of Neurology, Oradell Animal Hospital, 580 Winters Avenue, Paramus, NJ 07652, USA. ks56dvm@yahoo.com

Journal of Feline Medicine and Surgery
|April 25, 2009
PubMed
Summary

Feline seizures, while less common than in dogs, present diagnostic and treatment challenges. This review details a systematic approach and discusses novel antiepileptics for refractory feline seizure cases.

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Area of Science:

  • Veterinary Neurology
  • Feline Medicine
  • Epileptology

Background:

  • Seizures are a common neurological disorder in cats, encompassing focal and generalized types.
  • Causes are categorized into primary (idiopathic epilepsy) and secondary (structural lesions or metabolic disease).
  • Feline seizures affect all ages, with idiopathic epilepsy typically seen in younger cats (around 3.5 years) versus secondary causes (around 8 years).

Observation:

  • Refractory seizures in cats pose significant diagnostic and therapeutic hurdles for veterinarians.
  • A systematic diagnostic approach is crucial for identifying the underlying cause of feline seizures.
  • The literature on feline seizure treatment is less established than for canine epilepsy.

Findings:

  • Novel antiepileptic drugs, including levetiracetam, zonisamide, and pregabalin, show promise as add-on therapies.
  • These newer medications are particularly useful for feline cases refractory to phenobarbital.
  • Ongoing clinical trials are expanding treatment options for feline seizures.

Implications:

  • Veterinarians can utilize a structured approach to diagnose feline seizures more effectively.
  • Newer antiepileptic drugs offer advanced therapeutic options for challenging feline seizure cases.
  • This review provides essential guidance for managing feline seizures in emergency and general practice settings.