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P wave dispersion increases during hemodialysis sessions.
Beste Ozben1, Ahmet Toprak, Mehmet Koc
1Department of Cardiology, Marmara University School of Medicine, Istanbul, Turkey. bestes@doctor.com
Nephron. Clinical Practice
|April 25, 2009
Summary
Hemodialysis sessions significantly increase P wave dispersion (PWD), a marker for atrial fibrillation risk, in patients with chronic kidney disease. Predialysis blood pressure, potassium levels, and ultrafiltration predict this PWD increase.
Area of Science:
- Cardiology
- Nephrology
- Medical Electrocardiography
Background:
- Atrial fibrillation (AF) is prevalent in hemodialysis (HD) patients, contributing to high mortality.
- P wave dispersion (PWD) on electrocardiograms indicates AF risk.
Purpose of the Study:
- To investigate the impact of a hemodialysis session on P wave dispersion (PWD).
Main Methods:
- 25 patients undergoing chronic HD were studied.
- Electrocardiograms and blood samples were collected before, during (2nd hour), and after HD.
- PWD was calculated as the difference between maximum and minimum P wave durations.
Main Results:
- PWD significantly increased during HD sessions compared to predialysis values (41±12 ms vs. 21±10 ms).
- PWD correlated with predialysis blood pressure and serum potassium.
- Predialysis diastolic blood pressure, serum potassium, and ultrafiltration volume predicted prolonged PWD during HD.
Conclusions:
- Hemodialysis sessions lead to a significant increase in PWD.
- This increase may elevate the risk of AF episodes during HD.
- Predialysis diastolic blood pressure, serum potassium, and ultrafiltration are key predictors of PWD changes during HD.
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