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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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Hypertrophic cardiomyopathy and tachyarrhythmias detected by a pacemaker

Adrian Baranchuk1, Syamkumar Divakaramenon, Sebastian Ribas

  • 1Arrhythmia Service, Kingston General Hospital, Queen's, Canada. barancha@kgh.kari.net

Arquivos Brasileiros De Cardiologia
|April 25, 2009
PubMed

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Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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