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Updated: Jun 23, 2026
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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Cardiogenic shock caused by disulfiram
Ana Jerónimo1, Carla Meira, Augusta Amaro
1Serviço de Cuidados Intensivos, Hospital Pedro Hispano, Matosinhos, Portugal. anajeronimo@hotmail.com
Arquivos Brasileiros De Cardiologia
|April 25, 2009
Summary
Disulfiram intoxication can cause severe cardiogenic shock. Prompt diagnosis and treatment are crucial for managing this rare but potentially fatal condition in patients with disulfiram poisoning.
Area of Science:
- Toxicology
- Cardiology
- Pharmacology
Background:
- Disulfiram is used to deter alcohol consumption.
- Disulfiram intoxication is rare but can cause severe cardiovascular complications.
Observation:
- A case of a female patient with refractory shock after deliberate self-poisoning with disulfiram is presented.
- Clinical, biochemical, and echocardiographic assessments confirmed cardiogenic shock.
Findings:
- Disulfiram intoxication can lead to severe and potentially fatal cardiovascular manifestations, including cardiogenic shock.
- The case highlights refractory shock as a consequence of disulfiram overdose.
Implications:
- Clinicians should suspect disulfiram intoxication in cases of unexplained cardiogenic shock.
- Prompt and appropriate therapeutic interventions are essential for managing disulfiram-induced cardiovascular toxicity.
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