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Ovaries

Ovaries

The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of cuboidal...

Oogenesis

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...

Oogenesis

Oogenesis

Oogenesis, the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...

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Related Experiment Video

Updated: Jun 23, 2026

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Published on: October 28, 2021

Primary osteosarcoma of ovary.

Shamima Yeasmin¹, Kentaro Nakayama, Masako Ishibashi

¹Department of Obstetrics and Gynecology, Shimane University School of Medicine, 89-1 Enyacho, Izumo, Shimane, 693-8501, Japan.

International Journal of Clinical Oncology

|April 25, 2009

Summary

Primary ovarian osteosarcoma is a rare, aggressive cancer. Early surgical resection offers the best treatment hope for this malignant ovarian tumor.

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Area of Science:

Oncology
Gynecologic Oncology

Background:

Primary osteosarcoma of the ovary is an extremely rare and highly malignant tumor.
Few cases have been documented in medical literature over recent decades.

Observation:

A 50-year-old postmenopausal woman presented with a large abdominal mass, initially diagnosed as ovarian cancer.
The patient's disease was aggressive, showing no response to chemotherapy and resulting in death within one month.

Findings:

Histopathological examination of autopsy specimens confirmed a diagnosis of primary ovarian osteosarcoma.
This rare ovarian tumor presents as a rapidly progressing pelvic mass.

Implications:

Primary ovarian osteosarcoma must be considered in the differential diagnosis of large, rapidly progressing pelvic masses in postmenopausal women.
Complete surgical resection is the only currently promising treatment, underscoring the importance of early diagnosis.