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Genetic variability of wild-type measles viruses, circulating in the Russian Federation during the implementation of
S V Shulga1, P A Rota, J R Kremer
1G.N. Gabrichevsky Research Institute for Epidemiology and Microbiology, WHO European Reference Laboratory for Measles and Rubella, Moscow, Russia. s.shulga@gabrich.ru
Abstract:
Genetic characterization of wild-type measles viruses (MVs) is an important component of laboratory surveillance of measles. In this study, a phylogenetic analysis was performed of the nucleoprotein gene sequences of 228 MVs isolated in the Russian Federation between 2003 and 2007. Five genotypes, D4, D5, D6, D8, and H1, were detected. From 1999 through the first 6 months of 2003, the most prevalent genotype in the European part of Russia was D4. All genotype D4-type viruses were closely related to each other (with overall sequence diversity of
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