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Related Experiment Video

Updated: Jun 23, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Drug-eluting stenting: the case for post-dilation.

Enrico Romagnoli¹, Giuseppe M Sangiorgi, John Cosgrave

¹Emo Centro Cuore Columbus, Milan, Italy.

JACC. Cardiovascular Interventions

|April 28, 2009

Summary

This summary is machine-generated.

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Optimal stent expansion is crucial for successful percutaneous coronary interventions. High-pressure balloon post-dilation is often necessary to prevent complications like restenosis and stent thrombosis, especially with drug-eluting stents (DES).

Area of Science:

Interventional Cardiology
Cardiovascular Devices
Medical Imaging

Background:

Inadequate stent expansion post-percutaneous coronary intervention (PCI) is linked to higher rates of restenosis, target vessel revascularization, and stent thrombosis, particularly with drug-eluting stents (DES).
Despite advancements, suboptimal stent deployment remains a significant issue, occurring in 20-30% of cases, and even more frequently when assessed by intravascular ultrasound.

Purpose of the Study:

To review factors contributing to suboptimal stent delivery during PCI.
To emphasize the importance of high-pressure balloon post-dilation for achieving optimal stent expansion.
To highlight the impact of adequate expansion on reducing stent thrombosis and restenosis.

Main Methods:

Review of published literature on stent deployment and expansion.

Related Experiment Videos

Last Updated: Jun 23, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Analysis of anatomical, clinical, and device-related variables associated with suboptimal stent delivery.

Evaluation of the role of adjunctive high-pressure balloon dilation.

Main Results:

Suboptimal stent expansion is a common complication after PCI, increasing adverse clinical outcomes.
High-pressure balloon dilation is frequently required to achieve adequate minimum stent area and uniform expansion.
Evidence supports the use of post-dilation for both bare-metal stents and DES implantation.

Conclusions:

Achieving adequate stent expansion through techniques like high-pressure post-dilation is critical for improving long-term outcomes in PCI.
Addressing anatomical, clinical, and device-related risks can help minimize suboptimal stent delivery.
Optimal stent expansion positively influences the rates of stent thrombosis and restenosis.