Related Experiment Video
Updated: Jun 23, 2026
Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
Published on: January 22, 2022
The impact on ovarian reserve after laparoscopic ovarian cystectomy versus three-stage management in patients with
Dimitrios Tsolakidis1, George Pados, Dimitrios Vavilis
1Papageorgiou Hospital, 1st Department of Obstetrics & Gynecology, Aristotle University of Thessaloniki, North Efkarpia, Greece.
Objective:
To investigate the effect of two different laparoscopic methods on ovarian reserve in patients with ovarian endometriomas.
Design:
Prospective, randomized clinical trial.
Setting:
Endoscopy unit of a university hospital.
Patient(S):
Twenty women with endometriomas.
Intervention(S):
Patients were randomly selected to undergo either laparoscopic cystectomy for endometrioma (group 1) or the "three-step procedure" (group 2). Before and 6 months after laparoscopy all patients were evaluated, and 12 months postoperatively they underwent ultrasound scan examination.
Main Outcome Measure(S):
The primary end point was ovarian reserve damage based on the alterations of anti-Müllerian hormone (AMH). Secondary end points were the changes of antral follicle count and serum concentration of FSH, LH, E(2), and inhibin B.
Result(S):
Mean serum AMH was reduced significantly from 3.9-2.9 ng/mL in group 1 compared with the reduction from 4.5-3.99 ng/mL in group 2.
Conclusion(S):
Ovarian reserve determined by AMH is less diminished after the three-step procedure compared with cystectomy of endometriomas.
