Related Experiment Video
Updated: Jun 23, 2026

Isolation of Adipose Tissue Immune Cells
Published on: May 22, 2013
[Inflammation, adipokines and obesity]
1Service de nutrition, pôle d'endocrinologie, hôpital de la Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, U872 (équipe 7), Inserm, centre de recherche des Cordeliers, université Pierre-et-Marie-Curie Paris-6, 75006 Paris, France. karine.clement@psl.aphp.fr
Abstract:
In obese subjects, there is a "low grade" inflammatory state characterized by the moderate but chronic systemic rise of a panel of molecules (adipokines), which carry out, in addition to pro- or anti-inflammatory actions, several immune or metabolic functions, associated with a macrophagic infiltration in adipose tissue. These two factors provide a better understanding of the pathophysiology of obesity and its potential metabolic, cardiovascular or hepatic complications. A small or even moderate reduction of weight significantly reduces circulating inflammatory markers, modulates adipose tissue profile of inflammatory genes and the risks associated with obesity.
Related Concept Videos
Obesity
Inflammation
Chronic Inflammation: Introduction
Cholesterol: Significance and Regulation
Considering cholesterol and...
Hypodermis
Acute Inflammation III: Local and Systemic Effects

