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Published on: August 9, 2024
Optimizing CAD diagnosis in China with CT angiography
Mindy M Cheng1, Bin Lu, Sheng-Shou Hu
1University of Washington, Seattle, WA 98195, USA.
Insights
Coronary computed tomography angiography (CTA) combined with coronary angiography (CA) can save Chinese hospitals money and optimize patient selection for invasive procedures in diagnosing coronary artery disease (CAD). This approach improves cost-effectiveness and patient access to care.
Area of Science:
- Cardiovascular Imaging
- Health Economics
- Medical Technology Assessment
Background:
- Coronary artery disease (CAD) diagnosis in China faces challenges due to high prevalence and limited resources.
- Coronary computed tomography angiography (CTA) offers a potential solution to minimize invasive procedures for intermediate-risk patients.
- CTA can improve cost-effective diagnosis and patient access to CAD evaluation.
Purpose of the Study:
- To evaluate the cost and efficiency of using CTA in conjunction with CA for diagnosing suspected CAD in China.
- To optimize the diagnostic strategy for patients with intermediate pretest probability of significant CAD.
Main Methods:
- A cost-consequences analysis was performed from the perspective of Fuwai Hospital, Beijing.
- A decision-analytic model compared CA-only strategy versus CTA followed by CA strategy.
- The model focused on patients indicated for CA with intermediate pretest probability of significant CAD.
Main Results:
- The combined CTA and CA strategy resulted in cost savings of US $597 per patient compared to CA alone.
- The hospital cost per confirmed CAD diagnosis was US $8,103 for CTA-CA versus US $9,148 for CA-only.
- CTA sensitivity and CA unit cost were key influential parameters; cost savings ranged from US $461 to US $768 per patient.
Conclusions:
- Implementing CTA in China for intermediate-risk patients indicated for CA can optimize the selection for invasive procedures.
- This strategy may lead to significant cost savings for Chinese hospitals.
- CTA integration can enhance the efficiency and accessibility of CAD diagnosis.
Background:
Diagnosis of coronary artery disease (CAD) in China with coronary angiography (CA) can be challenging because of high disease prevalence and limited resources. Coronary computed tomography angiography (CTA) may provide an opportunity to minimize invasive diagnostic procedures among intermediate-risk patients indicated for CA and increase patient access to diagnosis of CAD in a cost-effective manner.
Objective:
This study was conducted to evaluate the potential costs and efficiency of using CTA in combination with CA to optimize diagnosis and care of patients with suspected CAD in China.
Methods:
We conducted a cost-consequences analysis from the perspective of Fuwai Hospital in Beijing. We developed a decision-analytic model that compared a diagnostic strategy of CA only with a strategy of CTA in combination with CA for patients with intermediate pretest probability of significant CAD and indicated for CA.
Results:
In the base-case analysis, use of CTA in combination with CA led to a cost-savings of US $597 per patient evaluated compared with the CA-only diagnostic strategy. The hospital cost per angiography-confirmed diagnosis of CAD was US $8,103 for CTA followed by CA compared with US $9,148 for CA only. The unit cost of CA, and CTA sensitivity were the most influential parameters on the results. The range of cost savings associated with use of CTA followed by CA was US $768 - US $461 per patient over a CAD prevalence range of 14% - 59%.
Conclusion:
The results of our study suggest that CTA implementation in China for intermediate-risk patients indicated for CA may optimize the patient population that undergoes invasive CA procedures and may provide cost savings for Chinese hospitals.
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