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Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
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Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
Crystal Field Theory - Tetrahedral and Square Planar Complexes02:46

Crystal Field Theory - Tetrahedral and Square Planar Complexes

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Crystal field theory (CFT) is applicable to molecules in geometries other than octahedral. In octahedral complexes, the lobes of the dx2−y2 and dz2 orbitals point directly at the ligands. For tetrahedral complexes, the d orbitals remain in place, but with only four ligands located between the axes. None of the orbitals points directly at the tetrahedral ligands. However, the dx2−y2 and dz2 orbitals (along the Cartesian axes) overlap with the ligands less than the dxy,...

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Related Experiment Video

Updated: Jun 23, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
22:10

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

Phase-locking of the 2D structures.

V V Apollonov, S Derzhavin, V Kislov

    Optics Express
    |April 28, 2009
    PubMed
    Summary
    This summary is machine-generated.

    Researchers achieved in-phase locking in wide aperture laser diode arrays using a quarter Talbot cavity. This method ensures system stability and selectivity, crucial for advanced laser applications.

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    Area of Science:

    • Optics and Photonics
    • Semiconductor Lasers

    Background:

    • Laser diode arrays are essential for high-power laser generation.
    • Achieving phase-locking in these arrays is critical for coherent beam combination.

    Purpose of the Study:

    • To investigate 1D and 2D phase-locking of wide aperture laser diode arrays.
    • To identify optimal conditions for achieving the preferred "in-phase" supermode.

    Main Methods:

    • Utilized an external quarter Talbot cavity (Lc=ZT/4=d^2/2λ).
    • Employed output mirror tilt at angle θm=λ/2d for supermode selection.
    • Analyzed parameters influencing phase-locking.

    Main Results:

    • Successfully demonstrated "in-phase" supermode selection in wide aperture laser diode arrays.
    • Confirmed system stability and adequate selectivity.
    • Validated findings for a fill factor (FF) of 0.6.

    Conclusions:

    • The quarter Talbot cavity with mirror tilt is an effective method for phase-locking laser diode arrays.
    • The system exhibits stability and selectivity suitable for practical applications.
    • Experimental results align with theoretical predictions.