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Optical tomography using the SCIRun problem solving environment: Preliminary results for three-dimensional geometries

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|April 28, 2009

Summary

This study introduces a 3D implementation of the TOAST imaging package within the SCIRun environment for advanced absorption and scatter reconstruction. This integration enhances interactive simulation and visualization for scientific computations.

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Area of Science:

Medical Imaging
Computational Science
Biomedical Engineering

Background:

Time-resolved optical imaging generates complex data requiring sophisticated reconstruction techniques.
Existing imaging packages may lack advanced 3D visualization and interactive simulation capabilities.
The SCIRun environment offers a powerful platform for developing and deploying scientific computations.

Purpose of the Study:

To present a 3D implementation of the UCL imaging package for absorption and scatter reconstruction from time-resolved data (TOAST).
To integrate TOAST within the SCIRun interactive simulation and visualization package.
To demonstrate the combined capabilities for 3D model reconstruction and analysis.

Main Methods:

Developed a 3D implementation of the TOAST package.
Embedded TOAST within the SCIRun computational workbench.
Utilized SCIRun's dataflow programming model for interactive simulation design and modification.
Applied the combined approach to reconstruct a segmented 3D head model.

Main Results:

Successfully integrated the TOAST imaging package into the SCIRun environment.
Demonstrated interactive 3D reconstruction of a segmented head model.
Showcased the ability to design, debug, and steer large-scale scientific computations.
Validated the utility of the combined TOAST/SCIRun approach for time-resolved optical imaging analysis.

Conclusions:

The integrated TOAST/SCIRun system provides a powerful and interactive platform for 3D absorption and scatter reconstruction.
This approach facilitates efficient simulation, visualization, and analysis of time-resolved optical imaging data.
The combined package offers significant advantages for researchers in biomedical optics and related fields.