Related Experiment Video
Updated: Jun 23, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Neighbourhood socioeconomic indicators and depressive symptoms in the Czech Republic: a population based study
Jitka Pikhartova1, Tarani Chandola, Ruzena Kubinova
1Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom. h.pikhart@ucl.ac.uk
Objectives:
Previous research shows only limited evidence on the contextual (neighbourhood-based) socioeconomic influences on mental health and depression. We investigated the association between individual and neighbourhood socioeconomic characteristics and depressive symptoms in the Czech Republic.
Methods:
Dichotomized CESD score of depressive symptoms was used as the outcome in a random sample of 3534 men and 4082 women aged 45-69 years in the Czech HAPIEE Study. 220 small areas were characterized by the proportion of university educated persons and the proportion of unemployed from the economically active population in the 2001 Census. Multilevel logistic regression was used for the analysis.
Results:
After controlling for individual-level variables, the effects of area-based characteristics were largely eliminated. The strongest area-based effect was that of the proportion of university educated persons; the ORs for 2(nd), 3(rd) and 4(th) quartile, compared with the 1(st) quartile, were 1.02, 0.93, and 0.82, respectively (p-value for trend 0.06). There were no cross-level interactions between socioeconomic variables.
Conclusions:
The effects of neighbourhood characteristics in this study were largely explained by individual socioeconomic variables.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depressive Disorders: MDD and Dysthymia
Depression: Overview
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Psychological and Sociocultural Causes of Schizophrenia
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
