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Severe factor X deficiency in a twin pregnancy
M Sinan Beksaç1, Zeliha Atak, Tülay Ozlü
1Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara, Turkey.
Archives of Gynecology and Obstetrics
|April 28, 2009
Summary
Factor X deficiency is a rare bleeding disorder. Prophylaxis with prothrombin complex concentrate can effectively manage severe cases, enabling successful pregnancies, as shown in this case study.
Area of Science:
- Hematology
- Genetics
- Obstetrics
Background:
- Factor X deficiency is a rare, autosomal recessive bleeding disorder.
- Severe cases present a significant bleeding phenotype, requiring management.
- Pregnancy in factor X-deficient patients poses management challenges.
Observation:
- A case of severe factor X deficiency during pregnancy was managed.
- The patient was carrying twins.
Findings:
- Prophylaxis with prothrombin complex concentrate was administered.
- The treatment effectively prevented bleeding complications.
Implications:
- Successful twin pregnancy was achieved in a severe factor X-deficient patient.
- This case highlights effective management strategies for factor X deficiency in pregnancy.
- Prothrombin complex concentrate is a viable option for managing factor X deficiency during gestation.
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