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Published on: June 18, 2021
Acute reversible Charles Bonnet syndrome precipitated by sudden severe anemia
Pierre-Francois Kaeser1, Francois-Xavier Borruat
1Hôpital Ophtalmique Jules Gonin, University of Lausanne, Lausanne, Switzerland.
Purpose:
To report the sudden onset of reversible Charles Bonnet syndrome precipitated byacute severe anemia.
Methods:
The charts of three patients (Usher syndrome, bilateral macular degeneration, and bilateral retinal vein occlusion) with acute Charles Bonnet syndrome in the setting of severe anemia were reviewed.
Results:
Anemia resulted from bladder surgery, recto-colitis, and severe urinary tract infection. Hemoglobin ranged from 78 to 86 g/L. Decreased visual acuity and formed visual hallucinations (giants, flowers, animals) were present in all three patients. Rapid reversal of Charles Bonnet syndrome and visual acuity improvement followed blood transfusion.
Conclusions:
Acute severe anemia can precipitate Charles Bonnet syndrome, which may be reversible by blood transfusion.
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