Natural evolution of regurgitation in healthy infants

Badriul Hegar1, Nita R Dewanti, Muzal Kadim

  • 1Department of Child Health, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Insights

Infant regurgitation is common in the first few months but typically resolves by 12 months. Frequent regurgitation can impact infant weight gain, with exclusively breastfed babies experiencing less spitting up.

Area of Science:

  • Pediatrics
  • Infant Health
  • Gastroenterology

Background:

  • Infant regurgitation, commonly known as spitting up, is a frequent occurrence in newborns.
  • Understanding its natural progression and influencing factors is crucial for pediatric care.

Purpose of the Study:

  • To investigate the natural history and prevalence of infant regurgitation throughout the first year of life.
  • To analyze the relationship between regurgitation frequency, feeding methods, and infant weight gain.

Main Methods:

  • Prospective recording of regurgitation frequency by parents for one week.
  • Follow-up of 130 infants for 12 months, with subgroup analysis based on feeding method.

Main Results:

  • Daily regurgitation was highest (73%) in the first month, decreasing to 50% by five months.
  • 20% of infants regurgitated over four times daily in the first two months; this reduced to 4% by 12 months.
  • Exclusively breastfed infants showed less regurgitation than partially breastfed infants, and frequent regurgitation affected weight gain, particularly in partially breastfed infants.

Conclusions:

  • Infant regurgitation is a common, self-limiting condition that generally resolves by 12 months of age.
  • High frequency of regurgitation (>4 times/day) in the first four months is associated with reduced weight gain.
  • Exclusive breastfeeding appears to be associated with a lower incidence of infant regurgitation.
Abstract

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