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Ankle-brachial index in HIV infection

Julián Olalla1, Daniel Salas, Javier de la Torre

  • 1Unidad de Medicina Interna, Hospital Costa del Sol, Marbella, Spain. julio.olalla@gmail.com

AIDS Research and Therapy
|April 29, 2009
PubMed

Prognosis for patients with the human immunodeficiency virus (HIV) has improved with the introduction of highly active antiretroviral therapy (HAART). Evidence over recent years suggests that the incidence of cardiovascular disease is increasing in HIV patients. The ankle-brachial index (ABI) is a cheap and easy test that has been validated in the general population. Abnormal ABI values are associated with increased cardiovascular mortality. To date, six series of ABI values in persons with HIV have been published, but none was a prospective study. No agreement exists concerning the risk factors for an abnormal ABI, though its prevalence is clearly higher in these patients than in the general population. Whether this higher prevalence of an abnormal ABI is associated with a higher incidence of vascular events remains to be determined.

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