Herceptin (trastuzumab) therapy in a twin pregnancy with associated oligohydramnios

Jennifer M A Beale1, Jeremy Tuohy, Simon J McDowell

  • 1Wellington Hospital, Obstetrics and Gynaecology, Wellington, New Zealand. jmab_12@hotmail.com

Herceptin (trastuzumab) is an adjuvant chemotherapy agent used in treatment of certain breast cancers. Limited information is available on the use of herceptin in pregnancy. This case is a twin pregnancy exposed to herceptin until 23 weeks' gestation. One twin had chronic renal failure develop, whereas the other twin did not.