Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 23, 2026

A Versatile Method of Patterning Proteins and Cells

A Versatile Method of Patterning Proteins and Cells

Published on: February 26, 2017

Patterned and switchable surfaces for biomolecular manipulation.

A L Hook¹, N H Voelcker, H Thissen

¹School of Chemistry, Physics and Earth Sciences, Flinders University, Adelaide 5001, Australia. Andrew.Hook@flinders.edu.au

Acta Biomaterialia

|April 29, 2009

Summary

Controlling biomolecule and cell behavior at solid interfaces is key for advanced biomedical devices. Patterned and switchable surfaces offer precise spatial and temporal manipulation for applications like biosensors and bioelectronics.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Fabrication of stimulus-responsive diatom biosilica microcapsules for antibiotic drug delivery.

Journal of materials chemistry. B·2020

Same author

Antibacterial properties of nitric oxide-releasing porous silicon nanoparticles.

Journal of materials chemistry. B·2020

Same author

IGF-2 coated porous collagen microwells for the culture of pancreatic islets.

Journal of materials chemistry. B·2020

Same author

New prebiotic chemistry inspired filter media for stormwater/greywater disinfection.

Journal of hazardous materials·2019

Same author

Rapid detection of nicotine from breath using desorption ionisation on porous silicon.

Chemical communications (Cambridge, England)·2017

Same author

Correction: Rapid fabrication of functionalised poly(dimethylsiloxane) microwells for cell aggregate formation.

Biomaterials science·2017

Area of Science:

Biomaterials Science
Surface Chemistry
Cell Biology

Background:

Biomolecule and cell interactions with solid surfaces are fundamental to biomedical applications.
Understanding these interactions enables precise spatial and temporal control over biological components.
This control drives the development of advanced devices like biosensors and bioelectronic components.

Purpose of the Study:

To review the behavior of biomolecules and cells at solid interfaces.
To highlight research on patterned and switchable surfaces for controlling these interactions.
To discuss the implications for developing advanced biomedical devices.

Main Methods:

Exploration of high-resolution patterning technologies (lithography, microprinting, microfluidics) for spatial control.

More Related Videos

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Cell Patterning on Photolithographically Defined Parylene-C: SiO₂ Substrates

Published on: March 7, 2014

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography

Published on: October 25, 2018

Related Experiment Videos

Last Updated: Jun 23, 2026

A Versatile Method of Patterning Proteins and Cells

A Versatile Method of Patterning Proteins and Cells

Published on: February 26, 2017

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Cell Patterning on Photolithographically Defined Parylene-C: SiO₂ Substrates

Published on: March 7, 2014

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography

Functional Surface-immobilization of Genes Using Multistep Strand Displacement Lithography

Published on: October 25, 2018

Investigation of switchable surface architectures for temporal control.

Analysis of the combined effects of patterned and switchable surfaces on biomolecule and cell behavior.

Main Results:

Patterned surfaces allow for precise spatial arrangement of biomolecules and cells.
Switchable surfaces enable dynamic temporal control over biological interactions.
The synergy of patterned and switchable surfaces provides unprecedented control at the solid-liquid interface.

Conclusions:

Advanced control over biomolecule and cell behavior at solid interfaces is achievable.
Patterned and switchable surfaces are crucial for next-generation biomedical devices.
Continued research in this area promises significant advancements in biosensing and bioelectronics.