Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
Phylogenetic Trees03:21

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.The length of the branches can depict time or the relative amount of change among organisms. For instance, the branch length might indicate the number of amino acid changes in the sequence that underlies the...
Phylogenetic Trees03:21

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.The length of the branches can depict time or the relative amount of change among organisms. For instance, the branch length might indicate the number of amino acid changes in the sequence that underlies the...
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
Phylogeny01:23

Phylogeny

Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spin-decoupled metasurfaces for polarization-tailored holography.

Optics express·2026
Same author

Postoperative breast function and quality of life follow-up study in patients with plasma cell mastitis: a 1-year longitudinal analysis.

Frontiers in medicine·2026
Same author

Clinical and EEG features integrated by a deep learning method to investigate treatment outcomes in epilepsy with eyelid myoclonia.

Seizure·2026
Same author

Health-Related Quality of Life and Family Impact Among Children with Epilepsy: The Role of Seizure Control.

Neuroepidemiology·2026
Same author

Microchromosome maintenance protein 2 is essential in immune infiltration-correlated prognosis of multiple myeloma patients by regulating cell cycle.

Cellular oncology (Dordrecht, Netherlands)·2026
Same author

PARS2 deficiency impairs mitochondrial homeostasis and activates ferroptotic to drive developmental and epileptic encephalopathy.

Free radical biology & medicine·2026

Related Experiment Video

Updated: Jun 23, 2026

Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing
10:18

Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing

Published on: October 16, 2018

CVTree update: a newly designed phylogenetic study platform using composition vectors and whole genomes.

Zhao Xu1, Bailin Hao

  • 1T-Life Research Center, Fudan University, 220 Handan Road, Shanghai 200433, China. xuzh.fdu@gmail.com

Nucleic Acids Research
|April 29, 2009
PubMed
Summary

The CVTree web server offers an efficient, alignment-free method for whole genome phylogenetic analysis. This updated tool aids in understanding evolutionary relationships with large genomic datasets.

More Related Videos

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Related Experiment Videos

Last Updated: Jun 23, 2026

Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing
10:18

Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing

Published on: October 16, 2018

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Traditional phylogenetic analysis relies on single or few genes.
  • Increasing genome data necessitates scalable and efficient analysis methods.
  • Alignment-free methods offer an alternative to sequence alignment challenges.

Purpose of the Study:

  • To introduce an enhanced CVTree web server for whole genome-based phylogenetic analysis.
  • To provide a user-friendly and efficient platform for analyzing large genomic datasets.
  • To offer an independent verification method for evolutionary relationship studies.

Main Methods:

  • Utilizes the alignment-free composition vector (CV) method for phylogenetic analysis.
  • Incorporates a database of over 850 prokaryotic and 80 fungal genomes.
  • Allows users to upload sequences for phylogenetic positioning within the database.

Main Results:

  • The new CVTree server is more efficient and user-friendly than previous versions.
  • Provides a faster and stable research platform for phylogenetic analysis.
  • Enables visualization of phylogenetic trees with collapsed monophyletic branches for taxonomic comparison.

Conclusions:

  • The CVTree web server is a valuable tool for modern phylogenetic research, accommodating large-scale genomic data.
  • Alignment-free, whole genome-based analysis provides a robust complement to traditional methods.
  • The enhanced features facilitate the comparison of evolutionary history with taxonomic classifications.