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Updated: Jan 25, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
[Bone fracture and the healing mechanisms. Molecular bases of fracture healing]
Masaki Noda1, Masashi Nagao, Ryo Hanyu
1Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University.
Abstract:
Fracture healing is a process comprising of a local bleeding followed by inflammation and differentiation of mesenchymal cells that lead to formation of soft extracellular matrix tissue, cartilage and bone. This pathway includes endo-chondral bone formation and in part intra-membranous bone formation. During this process several sets of cytokines are involved in the regulation of the progress in fracture healing. This paper reviews the molecules involved in fracture healing.
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