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Perivascular epithelioid cell tumor (PEComa) of abdominal cavity from falciform ligament: a case report

Cheol Woong Choi1, Tae Oh Kim, Kyung Yeob Kim

  • 1Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.

Journal of Korean Medical Science
|April 29, 2009
PubMed

Insights

This case study details a rare abdominal perivascular epithelioid cell tumor (PEComa) found in a Korean man. Surgical resection was successful, with no recurrence observed during follow-up.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Rare Tumors

Background:

  • Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms.
  • These tumors exhibit unique immunophenotypic co-expression of melanocytic and smooth muscle markers.
  • PEComas can occur in various anatomic locations, including the abdominal cavity.

Observation:

  • A 30-year-old Korean male presented with a growing abdominal mass.
  • The mass, located at the falciform ligament, measured 8.0x7.0x5.5 cm.
  • Histopathology revealed sheets of spindle-to-epithelioid cells with characteristic cytoplasm.

Findings:

  • Immunohistochemistry showed tumor cell positivity for HMB-45 (gp100), smooth muscle actin, and S-100.
  • These markers indicate a complex lineage, potentially involving melanocytic and neurogenic differentiation.
  • Radical tumor resection was performed without adjuvant therapy.

Implications:

  • This case highlights the successful surgical management of a rare abdominal PEComa.
  • Complete resection appears to be an effective treatment strategy for localized PEComas.
  • Further research into PEComa biology and optimal treatment protocols is warranted.
Keywords:
AngiomyolipomaLymphangiomyomatosisPerivascular Epithelioid Cell Neoplasms

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