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Major depression and personality disorder.

M Zimmerman1, B Pfohl, W H Coryell

  • 1Medical College of Pennsylvania, Eastern Pennsylvania Psychiatric Institute, Philadelphia 19129.

Journal of Affective Disorders
|August 1, 1991
PubMed
Summary
This summary is machine-generated.

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Depressed patients and their relatives showed similar rates of personality disorders (PDs) on interviews, but questionnaires indicated higher PD rates in patients. Interview assessments may be less sensitive to depression

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Mental Health Research

Background:

  • Previous research indicates high rates of personality disorders (PDs) in depressed patients.
  • Understanding PD prevalence in individuals with a history of depression is crucial for effective treatment.

Purpose of the Study:

  • To compare the prevalence and presentation of DSM-III personality disorders in depressed inpatients versus depressed relatives and never-ill controls.
  • To evaluate the sensitivity of interview-based versus self-report questionnaire assessments of PDs in the context of depression.

Main Methods:

  • Utilized the Structured Interview for DSM-III Personality Disorders (SIDP) and the Personality Disorders Questionnaire (PDQ) for assessment.
  • Compared PD rates and characteristics between depressed inpatients, depressed relatives, and never-ill controls with a history of major depression.

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Main Results:

  • Interview (SIDP) revealed similar PD rates between patients and relatives, except for higher borderline PD in inpatients.
  • Patients with PDs were more likely to have multiple PDs than relatives.
  • Questionnaire (PDQ) showed higher PD rates in the patient sample compared to interview results.
  • Borderline and histrionic patients presented more prototypically than relatives with the same PDs.

Conclusions:

  • Interview assessments of personality may be less sensitive to the state effects of depression than self-report questionnaires.
  • Findings extend the understanding of high PD rates in depression to a broader sample with a history of depression.
  • The choice of assessment method (interview vs. questionnaire) can significantly impact the estimated prevalence of PDs in depressed populations.