Higher genetic susceptibility to inflammation in mild disease activity of systemic lupus erythematosus
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Updated: Jun 23, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Li-Jen Tsai1, Sheng-Hsiung Hsiao, Jaw-Ji Tsai
1College of Engineering, National Taiwan University of Science and Technology, Taipei, 10672, Taiwan.
Abstract:
In order to test the hypothesis that stratification of Mexican Modification of the Systemic Lupus Erythematosus Disease Activity Index (MEX-SLEDAI) simplifies the genetic study of SLE, we evaluated the genetic susceptibility to inflammation and defects in clearance of immune complexes among SLE patients in Taiwan. SLE phenotypes were stratified according to the MEX-SLEDAI scores into two subgroups (
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