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Related Concept Videos

The Parathyroid Glands00:59

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Related Experiment Video

Updated: Jun 23, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Peripheral calcifying odontogenic cyst.

Maryam Seyedmajidi1, Maryam Feizabadi

  • 1Department of Oral and Maxillofacial Pathology, Dental Faculty, Babol University of Medical Sciences, Babol, Mazandaran, Iran. ms_majidi79@yahoo.com

Archives of Iranian Medicine
|April 30, 2009
PubMed
Summary
This summary is machine-generated.

Peripheral calcifying odontogenic cyst is a rare, less aggressive jaw cyst that appears as a gingival nodule. Simple excision biopsy is curative for this condition, which is histologically diagnosed by ghost cells.

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Last Updated: Jun 23, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Area of Science:

  • Odontogenic Cysts
  • Oral Pathology
  • Surgical Pathology

Background:

  • Calcifying odontogenic cyst (COC) is an uncommon odontogenic tumor, accounting for approximately 1% of all jaw cysts.
  • COCs can present as central (intraosseous) or peripheral (extraosseous) lesions.
  • Peripheral COCs are less frequent than central types.

Observation:

  • A case of peripheral calcifying odontogenic cyst (COC) is presented, located on the gingiva.
  • The lesion appeared as a painless, well-defined, sessile nodule, with a pink to reddish hue.
  • Peripheral COC predominantly affects older individuals compared to central COC.

Findings:

  • Histopathological examination revealed an epithelium characterized by the presence of numerous 'ghost cells'.
  • This characteristic histological feature is crucial for diagnosing peripheral COC.
  • Peripheral COC demonstrates less aggressive behavior compared to its central counterpart.

Implications:

  • Peripheral COC is a benign entity with a favorable prognosis.
  • A straightforward excision biopsy is a curative treatment for peripheral COC.
  • Early diagnosis and surgical management prevent recurrence and potential complications.