Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuronal Communication01:28

Neuronal Communication

Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
Neural Regulation01:37

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term safety and efficacy of intracortical microstimulation in humans.

Science translational medicine·2026
Same author

A framework for quantifying the mechanics of dexterous grasp.

bioRxiv : the preprint server for biology·2026
Same author

Observation-Related Activity in Human Motor Cortex Increases with Effector Anthropomorphicity.

bioRxiv : the preprint server for biology·2026
Same author

Limb state accounts for differences between motor imagery and action in motor cortex.

medRxiv : the preprint server for health sciences·2026
Same author

Evolutionarily conserved neural dynamics across mice, monkeys, and humans.

bioRxiv : the preprint server for biology·2026
Same author

Spatially Extensive LFP Correlations Identify Slow-Wave Sleep in Marmoset Sensorimotor Cortex.

eNeuro·2025

Related Experiment Video

Updated: Jun 23, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

The science of neural interface systems.

Nicholas G Hatsopoulos1, John P Donoghue

  • 1Department of Organismal Biology and Anatomy, and Committees on Computational Neuroscience and Neurobiology, University of Chicago, Chicago, Illinois 60637, USA. nicho@uchicago.edu

Annual Review of Neuroscience
|April 30, 2009
PubMed
Summary

Neural interfaces create links between the brain and external devices. Recording neural signals shows promise for helping paralyzed individuals and advancing brain function research.

More Related Videos

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
07:30

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

Published on: January 13, 2022

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology
09:58

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

Published on: July 21, 2018

Related Experiment Videos

Last Updated: Jun 23, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
07:30

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

Published on: January 13, 2022

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology
09:58

Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

Published on: July 21, 2018

Area of Science:

  • Neuroscience and Biomedical Engineering
  • Neural Interfaces and Brain-Computer Interfaces

Background:

  • Neural interface research aims to connect the nervous system with external devices.
  • While electrical stimulation is clinically established, neural recording interfaces for movement intention are emerging.
  • These technologies are crucial for assisting individuals with sensory, motor, or neural function disabilities.

Purpose of the Study:

  • To review state-of-the-art neural recording systems, particularly those capturing single-unit action potentials.
  • To explore the potential of neural interfaces in advancing fundamental understanding of brain function.
  • To identify technical and scientific challenges hindering widespread clinical adoption for severely motor-disabled patients.

Main Methods:

  • Review of current research and early-stage clinical neural recording systems.
  • Focus on systems capable of recording single-unit action potentials.
  • Analysis of the potential contributions to understanding neural coding, plasticity, brain-behavior relationships, and neurobiology of disease.

Main Results:

  • Early-stage clinical recording systems are beginning to show viability for aiding paralyzed individuals.
  • Neural recording interfaces offer unique insights into neural coding, plasticity, and brain-behavior relations.
  • Significant technical and scientific hurdles remain for broad clinical application.

Conclusions:

  • Neural recording interfaces represent a significant advancement in assistive technology for motor disabilities.
  • Further research and development are essential to overcome challenges and enable widespread adoption.
  • These systems hold immense potential for both clinical applications and fundamental neuroscience discovery.