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Updated: Jun 23, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
[Factors associated with adherence in HIV patients]
A Arrondo Velasco1, M L Sainz Suberviola, E M Andrés Esteban
1Servicio de Farmacia, Hospital de Navarra, Pamplona, Navarra, España. amaya2710@hotmail.com
Adherence to antiretroviral treatment (ARVT) in HIV patients is linked to better clinical outcomes. Factors like social support and treatment complexity significantly impact ARVT adherence.
Area of Science:
- Infectious Diseases
- Pharmacology
- Public Health
Context:
- HIV/AIDS management requires consistent antiretroviral therapy (ARVT).
- Assessing ARVT adherence is crucial for effective patient outcomes.
- Understanding factors influencing adherence is key to improving treatment strategies.
Purpose:
- To determine the relationship between ARVT adherence and clinical status in HIV patients.
- To identify factors contributing to poor adherence to ARVT.
- To evaluate the concordance between different adherence assessment methods.
Summary:
- This observational study assessed ARVT adherence in HIV patients using the SMAQ questionnaire and pharmacy dispensing records.
- Results showed an association between viral load and adherence, with non-adherence linked to social-familial environment and treatment complexity (pill burden).
- No concordance was found between the SMAQ questionnaire and dispensing records for adherence measurement.
Impact:
- Adherence to ARVT reduces the risk of virological failure in HIV patients.
- Identifying barriers to adherence, such as social support and treatment complexity, enables targeted interventions.
- Combining dispensing records with patient interviews offers a comprehensive approach to understanding and improving ARVT adherence.
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