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Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

J Nilsson1, J Skog, A Nordstrand

  • 1Department of Radiation Sciences, Oncology, Umeå University, Umea, Sweden. j.nilsson@vumc.nl

British Journal of Cancer
|April 30, 2009
PubMed

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Overview of Exosomes01:36

Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...