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Updated: Jun 23, 2026

Extraction of Non-Protein Amino Acids from Cyanobacteria for Liquid Chromatography-Tandem Mass Spectrometry Analysis
Published on: December 9, 2022
Bromoanaindolone, a novel antimicrobial exometabolite from the cyanobacterium Anabaena constricta
R-B Volk1, U Girreser, M Al-Refai
1Pharmaceutical Laboratories, Schaper & Bruemmer GmbH Co. KG, Salzgitter, Germany. volk@pharmazie.uni-kiel.de
Abstract:
A new brominated indole alkaloid, designated as bromoanaindolone, was isolated from culture media of the cyanobacterium Anabaena constricta and was identified as 6-bromo-3-hydroxy-3-methyl-indol-2-one with a slight excess of the (3R) enantiomer. The molecular structure was elucidated on the basis of IR, MS and NMR data. This extracellular metabolite of A. constricta possessed antimicrobial (anticyanobacterial and antibacterial) activity in different test systems, such as suspension and porous matrix tests.
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