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Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Antiprotozoal Agents01:21

Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...

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Related Experiment Video

Updated: Jun 23, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
11:36

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

Canine leishmaniasis in southeastern Spain.

Joaquina Martín-Sánchez1, Manuel Morales-Yuste, Carmen Acedo-Sánchez

  • 1Universidad de Granada, Granada, Spain. joaquina@ugr.es

Emerging Infectious Diseases
|May 1, 2009
PubMed
Summary

Canine leishmaniasis seroprevalence has increased over 22 years. Older, large dogs living outdoors in meso-Mediterranean areas face the highest risk of this parasitic disease.

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Area of Science:

  • Veterinary Parasitology
  • Epidemiology
  • Canine Health

Background:

  • Canine leishmaniasis (CanL) is a significant vector-borne parasitic disease.
  • Understanding prevalence changes and risk factors is crucial for disease control.
  • Previous studies indicated a need for updated epidemiological data.

Purpose of the Study:

  • To assess changes in canine leishmaniasis seroprevalence over time.
  • To identify key risk factors associated with CanL in a specific region.
  • To inform public health strategies for canine disease management.

Main Methods:

  • A cross-sectional seroprevalence study was conducted.
  • A survey was administered to dog owners.
  • Data were collected between April and June 2006.

Main Results:

  • Canine leishmaniasis seroprevalence showed an increase over a 22-year period.
  • The meso-Mediterranean bioclimatic level was identified as a high-risk area.
  • Risk factors included older age, larger body size, and outdoor living.

Conclusions:

  • Canine leishmaniasis prevalence is increasing in the studied region.
  • Environmental and host-specific factors significantly influence CanL risk.
  • Targeted interventions are needed for at-risk canine populations.