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Updated: Jun 23, 2026

Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System
Published on: May 8, 2020
[Sweetened solution intake in albino rats: taste versus calories]
Alma Gabriela Martínez Moreno1, Antonio López-Espinoza, Felipe de Jesús Díaz Reséndiz
1Centro de Investigaciones en Comportamiento Alimentario y Nutrición, Centro Universitario del Sur, Universidad de Guadalajara, Mexico. alma.martinez@cusur.udg.mx
Abstract:
Animals display preferences for sweetened over unsweetened foods under diverse experimental procedures. No evidence has been provided of whether flavor or energetic content of sweeteners determine this preference. In this experiment, female and male rats were exposed to water and a solution sweetened with glucose (sweet taste and calories) and water and a solution sweetened with sucralose (sweet taste without calories). We observed that animals exposed to glucose solution increased the sweetened water intake gradually compared to water intake and animals exposed to sucralose solution maintained equal sweetened water and water intake. This suggests that caloric content affects the increase of intake of sweetened liquids. However, it is important to continue to investigate whether history of taste exposure modifies water-intake response.
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