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Related Experiment Video

Updated: Jun 23, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Whole-body diffusion-weighted magnetic resonance imaging.

Thomas C Kwee¹, Taro Takahara, Reiji Ochiai

¹Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. thomaskwee@gmail.com

European Journal of Radiology

|May 1, 2009

Summary

Diffusion-weighted whole-body imaging (DWIBS) advances MRI for detecting and characterizing whole-body lesions. This technique enables routine clinical use for both cancer and non-cancerous conditions throughout the body.

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Area of Science:

Medical Imaging
Radiology
Biophysics

Background:

Diffusion-weighted magnetic resonance imaging (DWI) measures water molecule diffusivity.
Technological progress has led to diffusion-weighted whole-body imaging with background body signal suppression (DWIBS).

Purpose of the Study:

To review the principles and development of whole-body DWI.
To illustrate clinical applications of whole-body DWI.
To discuss limitations and challenges of whole-body DWI.

Main Methods:

Review of diffusion-weighted imaging principles.
Exploration of diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) development.
Analysis of clinical case studies and literature.

Main Results:

Whole-body DWI enables comprehensive detection and characterization of oncological and non-oncological lesions.
DWIBS facilitates routine clinical application of whole-body DWI.
The technique shows significant potential across various medical conditions.

Conclusions:

Whole-body DWI is a powerful tool for systemic disease evaluation.
Further research is needed to overcome current limitations and challenges.
Routine clinical implementation of DWIBS is becoming feasible.