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Updated: Jun 23, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
[Effect of leukotriene receptor antagonist on cough variant asthma]
Zhi-min He1, Yu-biao Guo, Can-mao Xie
1Department of Internal Medicine, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Objective:
To study the curative effect of leukotriene receptor antagonist on cough variant asthma (CVA).
Methods:
Sixty-four CVA patients received treatment with bricany and montelukas and 68 control patients had bricany treatment for 4 weeks. The recurrence rate was observed in the two groups during the follow-up for 6 months.
Results:
The remission time of two groups were 2.5-/+3.6 and 5.3-/+3.8 days in acute phase, respectively, showing a significant difference between them (P<0.05). The recurrence rate of the two groups within 6 months were 20.09% and 40.87%, respectively, showing also significantly differences (P<0.05).
Conclusion:
Leukotriene receptor antagonist and bricany can effectively control CVA and significantly lower the short-term recurrence rate of CVA.
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