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Updated: May 2, 2026

A Rat Model of Ventricular Fibrillation and Resuscitation by Conventional Closed-chest Technique
Published on: April 26, 2015
[Features of ischemic myocardial contracture after asphyxia-induced cardiac arrest in rats]
Li-min Xiao1, Xian-fu Sang, Dong-sheng Chen
1Experimental Teaching Center, Southern Medical University, Guangzhou 510515, China. xlm_98@hotmail.com
Objective:
To investigate the features of ischemic myocardial contracture after asphyxial cardiac arrest in rats.
Method:
Asphyxial cardiac arrest was induced in 8 Wistar rats, and the length and width of the heart were measured at the different time points after cardiac arrest.
Results:
Obvious ischemic myocardial contracture occurred after the cardiac arrest, reaching the maximal contracture at 4-6 min after the arrest.
Conclusions:
Ischemic myocardial contracture induced by asphyxia may be an important factor affecting the outcome of cardiopulmonary resuscitation.

