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Non-sporing anaerobes in hospital sepsis
C K Chakraborti1, B D Chatterjee, S N Sanyal
1Department of Bacteriology and Serology, School of Tropical Medicine, Calcutta.
Abstract:
In comparison to normal controls, the non-sporing anaerobes were often isolated from orodental sepsis (42% to 44.4%), chronic suppurative otitis media (40%), septic abortion (40.3%), uterocervical wound (45.4%), vaginitis (50%) and cancer cervix (50%). This was true (40%) in perforating ulcers of foot in leprosy. These organisms were less frequently noted in abdominal (11%) and episiotomy (22.8%) wounds and leucorrhoea (33.3%). The role of non-sporing anaerobes was also suggested by the high percentage ratio of number of isolates to number of cases and by its primary isolation in moderate to heavy number. Barring the cases of cancer cervix, the aerobic bacteria were the most common (78.8% to 100%) in all other conditions.
Insights
Non-sporing anaerobes are frequently found in various infections like orodental sepsis and vaginitis. Aerobic bacteria dominate most conditions, except for cancer cervix, where anaerobes play a significant role.
Area of Science:
- Microbiology
- Clinical Bacteriology
Background:
- Non-sporing anaerobes are increasingly recognized as significant pathogens.
- Understanding their prevalence in different human infections is crucial for effective treatment.
Purpose of the Study:
- To investigate the isolation frequency of non-sporing anaerobes in various clinical conditions.
- To compare the prevalence of anaerobic and aerobic bacteria in these conditions.
Main Methods:
- Bacteriological analysis of clinical samples from patients with diverse infections.
- Quantitative assessment of bacterial isolates, including non-sporing anaerobes and aerobic bacteria.
Main Results:
- Non-sporing anaerobes were frequently isolated from orodental sepsis (42-44.4%), chronic suppurative otitis media (40%), septic abortion (40.3%), uterocervical wounds (45.4%), vaginitis (50%), and cancer cervix (50%).
- These organisms were also found in leprosy foot ulcers (40%) but less so in abdominal (11%) and episiotomy wounds (22.8%), and leucorrhoea (33.3%).
- Aerobic bacteria were predominant (78.8-100%) in most conditions, except for cancer cervix.
Conclusions:
- Non-sporing anaerobes are significant contributors to various human infections, particularly in gynecological and orodental sites.
- The study highlights the differential prevalence of anaerobic and aerobic bacteria across different infection types, informing diagnostic and therapeutic strategies.