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Visual Agnosia01:12

Visual Agnosia

Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round end"...
Sign Test for Matched Pairs01:17

Sign Test for Matched Pairs

The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in value between...
Mismatch Repair01:20

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Mismatch Repair01:36

Mismatch Repair

Overview
Non-Verbal Cues01:29

Non-Verbal Cues

Non-verbal communication extends beyond gestures and facial expressions to include vocal elements known as paralanguage. Paralanguage consists of non-verbal vocal cues such as pitch, loudness, speech rate, pauses, and non-verbal vocalizations like laughter, sighs, and moans. These elements not only accompany speech but also provide critical emotional and contextual information.The Role of Paralanguage in CommunicationParalanguage adds depth to spoken language by conveying emotions and...
Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...

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Related Experiment Video

Updated: Jun 23, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Mismatch negativity with visual-only and audiovisual speech.

Curtis W Ponton1, Lynne E Bernstein, Edward T Auer

  • 1Compumedics/Neuroscan, Inc., 6605W W.T. Harris Blvd Suite F, Charlotte, NC 28269, USA.

Brain Topography
|May 1, 2009
PubMed
Summary

This study reveals visual speech processing begins early in the right temporal and parietal cortices using electroencephalography (EEG). These findings suggest a distinct visual pathway for phonetic cue extraction in speech perception.

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Interaction between Phonological and Semantic Processes in Visual Word Recognition using Electrophysiology
05:38

Interaction between Phonological and Semantic Processes in Visual Word Recognition using Electrophysiology

Published on: June 29, 2021

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Speech Processing

Background:

  • Cortical speech processing is traditionally viewed as hierarchical, moving from primary sensory areas outwards.
  • Early stages of visual speech perception remain incompletely understood, particularly the temporal dynamics and neural generators.

Purpose of the Study:

  • To investigate the early latency period of visual speech processing using electrophysiology.
  • To model the cortical generator locations of the mismatch negativity (MMN) response for visual speech.

Main Methods:

  • Utilized electroencephalography (EEG) to record brain activity.
  • Employed mismatch negativity (MMN) paradigms under visual-only (VO) and audiovisual (AV) conditions.
  • Applied current density reconstruction (CDR) to estimate MMN generator locations.

Main Results:

  • MMNs were observed at early latencies (82-87 ms) in response to visual speech stimuli.
  • MMN generators were localized to the right lateral temporal and parietal cortices.
  • These early latencies align with bottom-up visual processing principles.

Conclusions:

  • A dedicated visual pathway likely extracts phonetic cues from visible speech.
  • Early visual phonetic processing may modulate later auditory processing in speech perception.
  • Findings challenge purely auditory-centric models of early speech processing.