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[Percutaneous aortic valve replacement in high risk patients]
T Chatterjee1, C A Nienaber, H Schneider
1Abteilung für Kardiologie, Universitätsklinikum Rostock, Rostock.
Insights
Degenerative aortic stenosis, a common heart valve disease, affects many adults. Percutaneous aortic valve replacement offers a new durable treatment option for patients unsuitable for traditional surgery.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Degenerative, calcified aortic stenosis is the most prevalent form of adult valvular heart disease.
- Surgical aortic valve replacement is the standard treatment for eligible patients.
- Many patients are excluded from surgery due to advanced age and comorbidities, leading to unmet treatment needs.
Purpose of the Study:
- To highlight the challenges in treating aortic stenosis in elderly and comorbid patients.
- To introduce percutaneous aortic valve replacement as a novel therapeutic option.
Main Methods:
- Review of current treatment guidelines for aortic stenosis.
- Discussion of the evolution of treatment strategies.
- Focus on the advent and implications of percutaneous aortic valve replacement.
Main Results:
- Surgical aortic valve replacement is effective but not feasible for all patients.
- Percutaneous aortic valve replacement provides a viable alternative for high-risk surgical candidates.
- This minimally invasive approach expands treatment accessibility.
Conclusions:
- Percutaneous aortic valve replacement represents a significant advancement in managing aortic stenosis.
- It offers a durable and effective treatment for patients previously denied surgical intervention.
- The development signifies a new era in valvular heart disease therapy.
Abstract:
The degenerative, calcified aortic stenosis is the most common form of adult valvular heart disease. Surgical aortic valve replacement is the method of choice and can be performed at low risk in suitable candidates. However, a fair amount of patients is rejected from surgery due to old age and preexisting comorbidities increasing operative mortality. For this reason frequently operation is not accomplished. Today, with the development of percutaneous aortic valve replacement, the treatment of aortic stenosis has entered a new era providing a new durable treatment option.
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