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Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
Percutaneous closure of a postinfarction ventricular septal defect and an iatrogenic left ventricular free-wall
Parham Eshtehardi1, Ali Garachemani, Bernhard Meier
1Department of Cardiology, Bern University Hospital, Bern, Switzerland.
Insights
This study demonstrates successful percutaneous closure of a postinfarction ventricular septal defect and a left ventricular free-wall perforation in an elderly patient. Both defects were effectively treated in a single session using specialized occluders.
Area of Science:
- Cardiovascular Interventions
- Interventional Cardiology
- Structural Heart Disease
Background:
- Postinfarction ventricular septal defect (VSD) is a rare but serious complication of myocardial infarction.
- Percutaneous closure offers a less invasive alternative to surgical repair for VSDs.
- Complex cardiac defects require advanced interventional techniques.
Observation:
- An 83-year-old woman presented with a postinfarction VSD after anterior myocardial infarction and percutaneous coronary intervention.
- The patient experienced an iatrogenic left ventricular free-wall perforation during the VSD closure procedure.
- Two Amplatzer muscular VSD occluders were utilized for simultaneous defect closure.
Findings:
- Successful percutaneous closure of both the postinfarction VSD and the iatrogenic left ventricular free-wall perforation was achieved.
- The combined procedure was completed in a single interventional session.
- The use of Amplatzer devices facilitated the closure of these complex, coexisting defects.
Implications:
- Percutaneous closure is a viable and effective strategy for managing complex postinfarction VSDs, even with associated complications.
- This case highlights the potential for simultaneous closure of multiple cardiac defects during a single interventional procedure.
- Advanced device technology enables treatment of challenging structural heart conditions, improving patient outcomes.
Abstract:
A 83-year-old woman underwent percutaneous closure of postinfarction ventricular septal defect following anteroseptal myocardial infarction and percutaneous coronary intervention with stent implantation of the left anterior descending coronary artery. Postinfarction percutaneous ventricular septal defect closure was initially complicated by an iatrogenic left ventricular free-wall perforation. Both defects were closed using two Amplatzer muscular VSD occluders during the same session.

