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Investigating Intestinal Inflammation in DSS-induced Model of IBD

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Published on: February 1, 2012

Ramadan fasting and inflammatory bowel disease.

Hamid Tavakkoli¹, Saeid Haghdani, Mohammad Hassan Emami

¹Department of Gastroenterology, Al-Zahra Hospital, Isfahan, Iran. h_tavakoli@med.mui.ac.ir

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology

|May 2, 2009

Summary

Ramadan fasting appears safe for patients with inflammatory bowel disease (IBD). A study found no negative impact on disease severity, quality of life, or psychological state during Ramadan.

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Published on: February 27, 2014

Area of Science:

Gastroenterology
Internal Medicine
Clinical Nutrition

Background:

Ramadan fasting involves daily periods of fasting from dawn to sunset.
The physiological effects of Ramadan fasting on gastrointestinal health are not fully understood.
The impact of Ramadan fasting on patients with inflammatory bowel disease (IBD) remains unclear.

Purpose of the Study:

To assess the effect of Ramadan fasting on patients with IBD.
To evaluate changes in quality of life (QoL), psychological state, and disease severity during Ramadan.
To determine the safety and potential risks of Ramadan fasting for IBD patients in remission.

Main Methods:

A cohort study was conducted during Ramadan 2006.
Sixty IBD patients in remission voluntarily fasted.
QoL, psychological state, and disease severity were assessed before and after Ramadan.

Main Results:

No correlation was found between fasting duration and disease severity, QoL, or psychological state.
Overall QoL did not change significantly after Ramadan.
Anxiety scores decreased in women with ulcerative colitis (UC) (p=0.026).
Colitis activity index scores decreased in men with UC (p=0.008).
Younger UC patients fasted for more days than older patients (p=0.01).

Conclusions:

Ramadan fasting does not appear to pose significant risks for IBD patients in remission.
Fasting may be associated with improved psychological well-being and reduced disease activity in some UC patients.
Further research is warranted to explore the specific effects on different IBD subtypes and patient demographics.