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Published on: August 23, 2022
Congenital cardiac malformations in neonates with apparently isolated gastrointestinal malformations
Hasim Olgun1, Mehmet Karacan, Ibrahim Caner
1Department of Pediatrics, Division of Pediatric Cardiology, Faculty of Medicine, Atatörk University, Erzurum, Turkey. holgun@atauni.edu.tr
Insights
A significant number of newborns with gastrointestinal malformations also have congenital cardiac malformations (CCM). Early echocardiography screening for CCM is recommended in these infants to ensure timely treatment.
Area of Science:
- Pediatric Cardiology
- Neonatal Surgery
- Medical Diagnostics
Background:
- Congenital cardiac malformations (CCM) are known to be associated with gastrointestinal tract/abdominal wall malformations.
- Existing data often include specific conditions with high CCM rates, necessitating research on isolated cases.
- This study focuses on neonates with apparently isolated gastrointestinal malformations.
Purpose of the Study:
- To determine the incidence of congenital cardiac malformations (CCM) in neonates presenting with seemingly isolated gastrointestinal malformations.
- To investigate the prevalence of CCM in specific types of gastrointestinal malformations.
- To highlight the importance of early cardiac evaluation in neonates with gastrointestinal anomalies.
Main Methods:
- Echocardiography screening was performed on 201 neonates.
- Neonates included had apparently isolated malformations of the gastrointestinal tract/abdominal wall.
- Cardiac malformations were assessed in relation to specific gastrointestinal conditions.
Main Results:
- Congenital cardiac malformations (CCM) were diagnosed in 17.9% (36/201) of the neonates.
- Prevalence of CCM varied by gastrointestinal malformation: 15.9% with anal atresia, 23.7% with tracheoesophageal fistula/esophageal atresia, 8% with diaphragmatic hernia, and 29.4% with intestinal atresia.
- Approximately 30.6% of neonates with CCM had hemodynamically significant cardiac issues requiring intervention.
Conclusions:
- A substantial proportion of neonates with isolated gastrointestinal malformations exhibit congenital cardiac malformations (CCM).
- Early echocardiographic evaluation for CCM is crucial for neonates with gastrointestinal tract/abdominal wall malformations.
- Prompt cardiac assessment facilitates timely management and improves outcomes for affected infants.
Background:
The association of congenital cardiac malformations (CCM) with malformations of the gastrointestinal tract/abdominal wall is known. Nevertheless, the data presently available are derived from patient populations that include some special conditions known to be associated with a high rate of CCM. The aim of the present study was therefore to determine the incidence of cardiac malformations among neonates with apparently isolated malformations of the gastrointestinal tract/abdominal wall.
Methods:
A total of 201 neonates with apparently isolated gastrointestinal malformations were screened on echocardiography.
Result:
Thirty-six (17.9%) of the neonates were diagnosed as having a CCM. When the four most frequent gastrointestinal malformations were evaluated, a CCM was diagnosed in 11/69 (15.9%) with anal atresia, in 9/38 (23.7%) with tracheoesophageal fistula/esophageal atresia, in 2/25 (8%) with diaphragmatic hernia and in 5/17 (29.4%) with intestinal atresia. In 11 of 36 patients (30.6%) with CCM, the cardiac problems were hemodynamically significant, requiring anti-congestive and/or surgical treatment.
Conclusion:
A significant number of neonates with apparently isolated gastrointestinal malformations had CCM. Because almost all patients with malformations of the gastrointestinal tract/abdominal wall require early surgical intervention, they should be evaluated on echocardiography to investigate CCM at the earliest opportunity.
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