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Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

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Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model
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Single-embryo transfer versus multiple-embryo transfer.

Jan Gerris1

  • 1Centre for Reproductive Medicine, University Hospital Ghent, Ghent, Belgium. jan.gerris@ugent.be

Reproductive Biomedicine Online
|May 2, 2009
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Summary

Elective single-embryo transfer (eSET) can reduce multiple-birth risks in assisted reproduction. Careful patient selection and good embryo quality allow for reduced multiple pregnancies without significantly lowering live birth rates.

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Area of Science:

  • Reproductive Medicine
  • Obstetrics & Gynecology

Background:

  • Assisted reproductive technology (ART) has advanced, yet live birth rates remain suboptimal.
  • Multiple-embryo transfer (MET) is common but increases risks of multiple-order births, impacting maternal and infant health and incurring socio-economic costs.

Purpose of the Study:

  • To evaluate the benefits of elective single-embryo transfer (eSET) in reducing multiple pregnancies within ART.
  • To explore the potential of eSET to offer a safer and more cost-effective approach to assisted reproduction.

Main Methods:

  • Comparative studies analyzing outcomes of eSET versus MET in assisted reproduction.
  • Assessment of patient selection criteria and embryo quality in relation to pregnancy outcomes.

Main Results:

  • eSET can decrease the incidence of multiple-order pregnancies.
  • Careful patient selection and high-quality embryo transfer are key to maintaining live birth rates with eSET.
  • Studies suggest eSET can reduce risks without significantly compromising live birth rates.

Conclusions:

  • eSET presents a viable strategy to increase singleton pregnancies in ART, mitigating risks associated with multiple births.
  • Wider adoption of eSET requires addressing barriers like funding and physician/patient awareness.
  • eSET holds promise as a safer, potentially more cost-effective method for patients undergoing ART.