Arterial spin-labeled MR perfusion imaging: clinical applications

Area of Science:

• Radiology
• Medical Imaging
• Neuroimaging

Background:

• Arterial spin labeling (ASL) is emerging as a routine clinical perfusion imaging technique.
• ASL offers quantitative perfusion data without requiring intravenous contrast agents.
• It provides similar information to conventional dynamic susceptibility contrast (DSC) sequences.

Purpose of the Study:

• To highlight the increasing availability of ASL for routine clinical use.
• To emphasize the advantages of ASL, including quantification and lack of contrast agents.
• To guide interpretation of ASL perfusion imaging by detailing common pathological appearances.

Main Methods:

• Discussion of various ASL sequence parameter options.
• Analysis of how different ASL techniques influence the appearance of pathology.
• Review of common pathological findings in ASL perfusion imaging.

Main Results:

• ASL imaging is becoming widely available on clinical MR scanners.
• ASL allows for non-contrast enhanced, quantifiable perfusion assessment.
• Pathology visualization is dependent on the specific ASL technique employed.

Conclusions:

• ASL is a valuable, contrast-free tool for clinical perfusion imaging.
• Familiarity with ASL parameters and characteristic pathological patterns is essential for accurate interpretation.
• ASL facilitates improved diagnostic capabilities in perfusion assessment.