Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Graded Potential01:19

Graded Potential

Graded potentials are localized fluctuations in the cell membrane's electrical charge, commonly found in the dendrites of neurons. The magnitude of these potential changes depends on the strength of the initiating stimulus. In a membrane at its resting potential, a graded potential signifies a voltage shift either above -70 mV or below -70 mV.
Graded potentials fall into two categories: depolarizing and hyperpolarizing. Depolarizing graded potentials typically occur when sodium (Na+) or calcium...
Preparation of Samples for Electron Microscopy01:20

Preparation of Samples for Electron Microscopy

To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative wear behavior of lithium disilicate CAD/CAM ceramics under simulated mastication.

Dental materials : official publication of the Academy of Dental Materials·2026
Same author

MTFP1 drives pancreatic cancer liver metastatic colonisation by regulating mitochondrial metabolism reprogramming.

Gut·2026
Same author

Biomechanical Evaluation of Maxillary Central Incisors After Regenerative Endodontic Treatment: An Extended Finite Element Analysis.

Journal of endodontics·2025
Same author

On fracture modelling of implantable load-bearing bioceramic structures and its state of the art.

Acta biomaterialia·2025
Same author

Fracture load of feldspar ceramic crowns: effects of surface treatments and aging.

Clinical oral investigations·2025
Same author

The Calcium Hydroxide Controversy: Does Calcium Hydroxide Weaken Teeth?

Dental traumatology : official publication of International Association for Dental Traumatology·2024
Same journal

Five-Year Outcomes of Zirconia and Fiber-Reinforced Composite Cantilever Inlay-Retained Fixed Dental Prostheses with Different Retainer Designs: A Randomized Controlled Clinical Trial.

Journal of dentistry·2026
Same journal

ACCURACY OF 2D FACIAL PROFILE PHOTOGRAPHS UNDER ROUTINE CLINICAL CONDITIONS COMPARED WITH 3D IMAGING.

Journal of dentistry·2026
Same journal

Adhesion of resin composites to 3D-printed dental resins: A study on the effect of surface conditioning methods and repair materials.

Journal of dentistry·2026
Same journal

DGADS: A Graph-based Agentic Decision Support System for Precision Dental Question Answering.

Journal of dentistry·2026
Same journal

Preventive Effects of a Strontium‑Containing Nano Bioactive Glass Hydrogel Against Enamel Caries: An In Vitro Study.

Journal of dentistry·2026
Same journal

Does robotic surgery offer the highest accuracy for delayed implant placement in single-tooth spaces? A network meta-analysis of randomized clinical trials.

Journal of dentistry·2026
See all related articles

Related Experiment Video

Updated: Jun 23, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

Enamel--a functionally graded natural coating.

Li-Hong He1, Michael V Swain

  • 1Department of Oral Rehabilitation, Faculty of Dentistry, University of Otago, New Zealand. lihong.he@otago.ac.nz

Journal of Dentistry
|May 2, 2009
PubMed
Summary
This summary is machine-generated.

Tooth enamel exhibits graded mechanical properties, with inner regions being softer but better at stress redistribution than outer regions. This natural gradient design offers insights for developing advanced functional materials.

More Related Videos

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography
06:53

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography

Published on: January 25, 2019

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
09:56

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications

Published on: December 8, 2015

Related Experiment Videos

Last Updated: Jun 23, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
08:26

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography
06:53

Additive Manufacturing of Functionally Graded Ceramic Materials by Stereolithography

Published on: January 25, 2019

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
09:56

Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications

Published on: December 8, 2015

Area of Science:

  • Biomaterials Science
  • Dental Materials
  • Materials Science

Background:

  • Tooth enamel is the hardest biological tissue, crucial for masticatory function.
  • Understanding its structural-property relationships is key to biomimetic material design.

Purpose of the Study:

  • To investigate the graded mechanical properties of human tooth enamel from the outer to inner regions.
  • To correlate these properties with compositional and microstructural variations.
  • To explore the functional implications of enamel's natural gradient design.

Main Methods:

  • Nanoindentation was used to assess mechanical properties like elastic modulus and hardness.
  • Raman spectroscopy and Scanning Electron Microscopy (SEM) analyzed compositional and microstructural differences.
  • Properties evaluated included creep, stress redistribution, and energy absorption.

Main Results:

  • Inner enamel demonstrated lower elastic modulus and hardness compared to outer enamel.
  • Inner enamel exhibited superior indentation creep and stress redistribution capabilities.
  • These variations are attributed to gradual compositional and microstructural changes across the enamel depth.

Conclusions:

  • Enamel functions as a natural, functionally graded biocomposite material.
  • Its unique structure significantly influences the mechanical behavior of teeth and dental restorations.
  • Nature's design provides a valuable model for developing advanced functional graded materials and coatings.